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KMID : 0366220060410030204
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Korean Journal of Hematology
2006 Volume.41 No. 3 p.204 ~ p.207
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Evans Syndrome following T Cell-repleted Unrelated Bone Marrow Transplantation for Myelodysplastic Syndrome: Successful Response to High-dose Corticosteroid
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Lee Young-Ho
Kim Young-Dae
Kim Yeong-Myung
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Abstract
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Evans syndrome after hematopoietic stem cell transplantation rarely occurs and this condition is refractory to treatment, particularly in childhood. We experienced a case of Evans syndrome following unmanipulated unrelated bone marrow transplantation. Evans syndrome developed at early post-transplantation period (day +42) and it responded very well to high-dose corticosteroid. Autoimmune cytopenia should be considered for post-engraftment cytopenias and high-dose corticosteroid therapy might be considered as a treatment of the early onset type of autoimmune cytopenia that can occur after hematopoietic stem cell transplantation.
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KEYWORD
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Evans syndrome, T cell repleted bone marrow transplantation, High-dose corticosteroid
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